AlphaFold is an advanced artificial intelligence system developed by DeepMind, a subsidiary of Google, that specializes in protein folding prediction. Launched in 2020, AlphaFold represents a significant breakthrough in the field of structural biology. By accurately predicting the three-dimensional structure of proteins from their amino acid sequences, AlphaFold addresses one of the most challenging problems in biology. Its predictions provide invaluable insights into protein structure and function, with implications for drug discovery, understanding diseases, and designing novel enzymes. AlphaFold’s success stems from its innovative application of deep learning techniques, including neural networks and attention mechanisms, trained on vast databases of protein structures. Its performance in the biennial Critical Assessment of Structure Prediction (CASP) competition demonstrated unprecedented accuracy, surpassing previous state-of-the-art methods and revolutionizing our ability to decipher the molecular machinery of life.